• 2024
    • Drent, M., Wijnen, P., Bekers, O., & Bast, A. (2024). Is a Vitamin K Epoxide Reductase Complex Subunit 1 (VKORC1) Polymorphism a Risk Factor for Nephrolithiasis in Sarcoidosis?International Journal of Molecular Sciences, 25(8), Article 4448. https://doi.org/10.3390/ijms25084448
    • Janssen, S. L. J. E., de Vries, F., Mingels, A. M. A., Kleinnibbelink, G., Hopman, M. T. E., Mosterd, A., Velthuis, B. K., Aengevaeren, V. L., & Eijsvogels, T. M. H. (2024). Exercise-induced cardiac troponin release in athletes with versus without coronary atherosclerosis. American Journal of Physiology-heart and Circulatory Physiology, 326(4), H1045-H1052. https://doi.org/10.1152/ajpheart.00021.2024
    • Drent, M., Wijnen, P. A., Jessurun, N. T., Harmsze, A. M., Bekers, O., & Bast, A. (2024). Drug-Gene Risk Stratification in Patients with Suspected Drug-Induced Interstitial Lung Disease. Drug Safety, 47(4), 355-363. https://doi.org/10.1007/s40264-024-01400-0
    • Aydeniz, E., van Rosmalen, F., de Kok, J., Martens, B., Mingels, A. M. A., Canakci, M. E., Mihl, C., Vernooy, K., Prinzen, F. W., Wildberger, J. E., van der Horst, I. C. C., van Bussel, B. C. T., & Driessen, R. G. H. (2024). The association between coronary artery calcification and vectorcardiography in mechanically ventilated COVID-19 patients: the Maastricht Intensive Care COVID cohort. Intensive Care Medicine Experimental, 12(1), 26. https://doi.org/10.1186/s40635-024-00611-0
    • Aakre, K. M., Apple, F. S., Mills, N. L., Meex, S. J. R., Collinson, P. O., & International Federation of Clinical Chemistry Committee on Clinical Applications of Cardiac Biomarkers (IFCC C-CB) (2024). Lower Limits for Reporting High-Sensitivity Cardiac Troponin Assays and Impact of Analytical Performance on Patient Misclassification. Clinical Chemistry, 70(3), 497-505. Article hvad185. https://doi.org/10.1093/clinchem/hvad185
    • van Doorn, W. P. T. M., Helmich, F., van Dam, P. M. E. L., Jacobs, L. H. J., Stassen, P. M., Bekers, O., & Meex, S. J. R. (2024). Explainable Machine Learning Models for Rapid Risk Stratification in the Emergency Department: A Multicenter Study. Journal of Applied Laboratory Medicine, 9(2), 212-222. Article jfad094. https://doi.org/10.1093/jalm/jfad094
    • Todaro, A. M., Radu, C. M., Ciccone, M., Toffanin, S., Serino, M. L., Campello, E., Bulato, C., Lunghi, B., Gemmati, D., Cuneo, A., Hackeng, T. M., Simioni, P., Bernardi, F., & Castoldi, E. (2024). In vitro and ex vivo rescue of a nonsense mutation responsible for severe coagulation factor V deficiency. Journal of Thrombosis and Haemostasis, 22(2), 410-422. https://doi.org/10.1016/j.jtha.2023.10.007
    • Arfman, T., Zollet, V., van Es, N., Bosch, F. T. M., Nicolaes, G. A. F., Sorvillo, N., & Voorberg, J. (2024). Elevated levels of citrullinated fibrinogen in patients with cancer. eJHaem, 5(1), 136-140. https://doi.org/10.1002/jha2.825
    • Reutelingsperger, C. P. M., Gijbels, M. J., Spronk, H., Van Oerle, R., Schrijver, R., Ekhart, P., de Kimpe, S., & Nicolaes, G. A. F. (2024). M6229 Protects against Extracellular-Histone-Induced Liver Injury, Kidney Dysfunction, and Mortality in a Rat Model of Acute Hyperinflammation. International Journal of Molecular Sciences, 25(3), Article 1376. https://doi.org/10.3390/ijms25031376
    • van Dam, P. M. E. L., van Doorn, W. P. T. M., van Gils, F., Sevenich, L., Lambriks, L., Meex, S. J. R., Cals, J. W. L., & Stassen, P. M. (2024). Machine learning for risk stratification in the emergency department (MARS-ED) study protocol for a randomized controlled pilot trial on the implementation of a prediction model based on machine learning technology predicting 31-day mortality in the emergency department. Scandinavian Journal of Trauma Resuscitation & Emergency Medicine, 32(1), Article 5. https://doi.org/10.1186/s13049-024-01177-2
    • de Kok, J. W. T. M., van Rosmalen, F., Koeze, J., Keus, F., van Kuijk, S. M. J., Castela Forte, J., Schnabel, R. M., Driessen, R. G. H., van Herpt, T. T. W., Sels, J.-W. E. M., Bergmans, D. C. J. J., Lexis, C. P. H., van Doorn, W. P. T. M., Meex, S. J. R., Xu, M., Borrat, X., Cavill, R., van der Horst, I. C. C., & van Bussel, B. C. T. (2024). Deep embedded clustering generalisability and adaptation for integrating mixed datatypes: two critical care cohorts. Scientific Reports, 14(1), Article 1045. https://doi.org/10.1038/s41598-024-51699-z
    • Guerkan, B., Poelman, H., Pereverzeva, L., Kruijswijk, D., de Vos, A. F., Groenen, A. G., Nollet, E. E., Wichapong, K., Lutgens, E., van der Poll, T., Du, J., Wiersinga, W. J., Nicolaes, G. A. F., & van 't Veer, C. (2024). The IRAK-M death domain: a tale of three surfaces. Frontiers in Molecular Biosciences, 10, Article 1265455. https://doi.org/10.3389/fmolb.2023.1265455
    • Mohapatra, A. K., Todaro, A. M., & Castoldi, E. (2024). Factor V variants in bleeding and thrombosis. Research and practice in thrombosis and haemostasis, 8(1), Article 102330. Advance online publication. https://doi.org/10.1016/j.rpth.2024.102330
  • 2023
    • van Dam, P. M. E. L., Lievens, S., Zelis, N., van Doorn, W. P. T. M., Meex, S. J. R., Cals, J. W. L., & Stassen, P. M. (2023). Head-to-head comparison of 19 prediction models for short-term outcome in medical patients in the emergency department: a retrospective study. Annals of Medicine, 55(2), Article 2290211. https://doi.org/10.1080/07853890.2023.2290211
    • Huckriede, J. B., Beurskens, D. M. H., Wildhagen, K. C. C. A., Reutelingsperger, C. P. M., Wichapong, K., & Nicolaes, G. A. F. (2023). Design and characterization of novel activated protein C variants for the proteolysis of cytotoxic extracellular histone H3. Journal of Thrombosis and Haemostasis, 21(12), 3557-3567. https://doi.org/10.1016/j.jtha.2023.08.023
    • Jukema, B. N., Pelgrim, T. C., Janssen, S. L. J. E., Eijsvogels, T. M. H., Mingels, A., Vroemen, W., Vrisekoop, N., & Koenderman, L. (2023). Exercise-induced eosinophil responses: Normal cell counts with a marked decrease in responsiveness. Clinical and Translational Allergy, 13(11), Article e12314. https://doi.org/10.1002/clt2.12314
    • Van de Berg, T. W., Beckers, E. A. M., Heubel-Moenen, F. C. J. I., Henskens, Y. M. C., Thomassen, M. C. L. G. D., & Hackeng, T. M. (2023). Sensitive Measurement of Clinically Relevant Factor VIII Levels in Thrombin Generation Assays Requires Presence of Factor XIa. Thrombosis and Haemostasis, 123(11), 1034-1041. https://doi.org/10.1055/a-2101-7961
    • Timmers, M., Peeters, W., Hauwert, N. J., Rijcken, C. J. F., Vermonden, T., Dijkgraaf, I., & Liskamp, R. M. J. (2023). Specific N-terminal attachment of TMTHSI linkers to native peptides and proteins for strain-promoted azide alkyne cycloaddition. Chemical Communications, 59(76), 11397-11400. Article 59. https://doi.org/10.1039/d3cc03397j
    • Mingels, A., Mills, N. L., Mueller, C., & Study Group on Biomarkers of the ESC Association for Acute CardioVascular Care (2023). Cardiac troponin T and I: back to basics. European Heart Journal: Acute Cardiovascular Care, 12(9), 631–632. Article zuad084. https://doi.org/10.1093/ehjacc/zuad084
    • Denessen, E. J. S., Vroemen, W. H. M., Litjens, E. J. R., Henskens, Y. M. C., van der Sande, F. M., Bekers, O., de Boer, D., & Mingels, A. M. A. (2023). Cardiac Troponin T Degradation in End-Stage Renal Disease Patients Appears to Occur in Vivo. Journal of Applied Laboratory Medicine, 8(5), 1000-1002. https://doi.org/10.1093/jalm/jfad043
    • Schönichen, C., Montague, S. J., Brouns, S. L. N., Burston, J. J., Cosemans, J. M. E. M., Jurk, K., Kehrel, B. E., Koenen, R. R., Ní Áinle, F., O'Donnell, V. B., Soehnlein, O., Watson, S. P., Kuijpers, M. J. E., Heemskerk, J. W. M., & Nagy, M. (2023). Antagonistic Roles of Human Platelet Integrin aIIbβ3 and Chemokines in Regulating Neutrophil Activation and Fate on Arterial Thrombi Under Flow. Arteriosclerosis Thrombosis and Vascular Biology, 43(9), 1700-1712. https://doi.org/10.1161/ATVBAHA.122.318767
    • Chai, J., Wu, J., Li, J., Liao, H., Lu, W., Guo, R., Shao, Z., Jmel, M. A., Martins, L. A., Hackeng, T., Ippel, H., Dijkgraaf, I., Kotsyfakis, M., & Xu, X. (2023). Novel Amphibian Bowman-Birk-Like Inhibitor with Antioxidant and Anticoagulant Effects Ameliorates Pancreatitis Symptoms in Mice. Journal of Medicinal Chemistry, 66(17), 11869-11880. https://doi.org/10.1021/acs.jmedchem.3c00475
    • Hendriks, F. K., Trommelen, J., van der Sande, F. M., van Kranenburg, J. M. X., Kuijpers, J. H. W., Houtvast, D. C. J., Jetten, G. H. J., Goessens, J. P. B., Meex, S. J. R., Kooman, J. P., & van Loon, L. J. C. (2023). Branched-chain ketoacid co-ingestion with protein lowers amino acid oxidation during hemodialysis: A randomized controlled cross-over trial. Clinical Nutrition, 42(8), 1436-1444. https://doi.org/10.1016/j.clnu.2023.06.034
    • Timmers, M., Kipper, A., Frey, R., Notermans, S., Voievudskyi, M., Wilson, C., Hentzen, N., Ringle, M., Bovino, C., Stump, B., Rijcken, C. J. F., Vermonden, T., Dijkgraaf, I., & Liskamp, R. (2023). Exploring the Chemical Properties and Medicinal Applications of Tetramethylthiocycloheptyne Sulfoximine Used in Strain-Promoted Azide-Alkyne Cycloaddition Reactions. Pharmaceuticals, 16(8), Article 1155. https://doi.org/10.3390/ph16081155
    • Wang, R., Damanik, F., Kuhnt, T., Jaminon, A., Hafeez, S., Liu, H., Ippel, H., Dijkstra, P. J., Bouvy, N., Schurgers, L., ten Cate, A. T., Dias, A., Moroni, L., & Baker, M. B. (2023). Biodegradable Poly(ester) Urethane Acrylate Resins for Digital Light Processing: From Polymer Synthesis to 3D Printed Tissue Engineering Constructs. Advanced Healthcare Materials, 12(17), Article 2202648. https://doi.org/10.1002/adhm.202202648
    • Danckwardt, S., Tregouet, D.-A., & Castoldi, E. (2023). Post-transcriptional control of haemostatic genes: mechanisms and emerging therapeutic concepts in thrombo-inflammatory disorders. Cardiovascular Research, 119(8), 1624-1640. https://doi.org/10.1093/cvr/cvad046
    • Alaour, B., Kaier, T. E., Hasselbalch, R. B., van Doorn, W., Meex, S., & Marber, M. (2023). Direct Comparison of the Circadian Rhythm of Cardiac Myosin-Binding Protein C (cMyC) and Cardiac Troponin. Journal of Applied Laboratory Medicine, 8(4), 831-834. https://doi.org/10.1093/jalm/jfad025
    • Aakre, K. M., Meex, S. J. R., & Mills, N. L. (2023). Cardiac Troponin Reporting in Children and Young Adults: Time to Change Clinical Practice. Circulation, 148(1), 17-19. https://doi.org/10.1161/CIRCULATIONAHA.123.065297
    • Castoldi, E. (2023). Making sense of FV short. Blood, 141(26), 3134-3135. https://doi.org/10.1182/blood.2023020274
    • Dai, L., Mafra, D., Shiels, P. G., Hackeng, T. M., Stenvinkel, P., & Schurgers, L. J. (2023). Vitamin K and Hallmarks of Ageing: Focus on Diet and Gut Microbiome. Nutrients, 15(12), Article 2727. https://doi.org/10.3390/nu15122727
    • Thomassen, M. C. L. G. D., Bouwens, B. R. C., Wichapong, K., Suylen, D. P., Bouwman, F. G., Hackeng, T. M., & Koenen, R. R. (2023). Protein arginine deiminase 4 inactivates tissue factor pathway inhibitor-alpha by enzymatic modification of functional arginine residues. Journal of Thrombosis and Haemostasis, 21(5), 1214-1226. https://doi.org/10.1016/j.jtha.2023.01.017
    • Denessen, E. J. S., Nass, S. I. J., Bekers, O., Vroemen, W. H. M., & Mingels, A. M. A. (2023). Circulating forms of cardiac troponin: a review with implications for clinical practice. Journal of Laboratory and Precision Medicine, 8(1), Article A3. https://doi.org/10.21037/jlpm-22-66
    • de Winther, M. P. J., Bäck, M., Evans, P., Gomez, D., Goncalves, I., Jørgensen, H. F., Koenen, R. R., Lutgens, E., Norata, G. D., Osto, E., Dib, L., Simons, M., Stellos, K., Ylä-Herttuala, S., Winkels, H., Bochaton-Piallat, M.-L., & Monaco, C. (2023). Translational opportunities of single-cell biology in atherosclerosis. European Heart Journal, 44(14), 1216-1230. https://doi.org/10.1093/eurheartj/ehac686
    • Abbas, M. N., Jmel, M. A., Mekki, I., Dijkgraaf, I., & Kotsyfakis, M. (2023). Recent Advances in Tick Antigen Discovery and Anti-Tick Vaccine Development. International Journal of Molecular Sciences, 24(5), Article 4969. https://doi.org/10.3390/ijms24054969
    • Chabronova, A., van den Akker, G. G. H., Housmans, B. A. C., Caron, M. M. J., Cremers, A., Surtel, D. A. M., Wichapong, K., Peffers, M. M. J., van Rhijn, L. W., Marchand, V., Motorin, Y., & Welting, T. J. M. (2023). Ribosomal RNA-based epitranscriptomic regulation of chondrocyte translation and proteome in osteoarthritis. Osteoarthritis and Cartilage, 31(3), 374-385. https://doi.org/10.1016/j.joca.2022.12.010
    • Tore, E. C., Elshorbagy, A. K., Bakers, F. C. H., Brouwers, M. C. G. J., Dagnelie, P. C., Eussen, S. J. P. M., Jansen, J. F. A., Kooi, M. E., Kusters, Y. H. A. M., Meex, S. J. R., Olsen, T., Refsum, H., Retterstøl, K., Schalkwijk, C. G., Stehouwer, C. D. A., Vinknes, K. J., & van Greevenbroek, M. M. J. (2023). Associations between plasma sulfur amino acids and specific fat depots in two independent cohorts: CODAM and The Maastricht Study. European Journal of Nutrition, 62(2), 891-904. https://doi.org/10.1007/s00394-022-03041-4
    • Hendriks, F. K., Kuijpers, J. H. W., van Kranenburg, J. M. X., Senden, J. M. G., van der Sande, F. M., Kooman, J. P., Meex, S. J. R., & van Loon, L. J. C. (2023). Intradialytic protein ingestion and exercise do not compromise uremic toxin removal throughout hemodialysis. Journal of Renal Nutrition, 33(2), 376-385. https://doi.org/10.1053/j.jrn.2022.07.006
    • de Vries, F., Huckriede, J., Wichapong, K., Reutelingsperger, C., & Nicolaes, G. A. F. (2023). The role of extracellular histones in COVID-19. Journal of Internal Medicine, 293(3), 275-292. https://doi.org/10.1111/joim.13585
    • Koenen, R. R. (2023). Platelets: from simple fragments to inflammation regulators. European Heart Journal, 44(8), 633-635. https://doi.org/10.1093/eurheartj/ehac705
    • Pavlic, A., Poelman, H., Wasilewski, G., Wichapong, K., Lux, P., Maassen, C., Lutgens, E., Schurgers, L. J., Reutelingsperger, C. P., & Nicolaes, G. A. F. (2023). Inhibition of Neutral Sphingomyelinase 2 by Novel Small Molecule Inhibitors Results in Decreased Release of Extracellular Vesicles by Vascular Smooth Muscle Cells and Attenuated Calcification. International Journal of Molecular Sciences, 24(3), Article 2027. https://doi.org/10.3390/ijms24032027
    • Yao, T. Y., Chen, H. L., Wang, R., Rivero, R., Wang, F. Y., Kessels, L., Agten, S. M., Hackeng, T. M., Wolfs, T. G. A. M., Fan, D. D., Baker, M. B., & Moroni, L. (2023). Thiol-ene conjugation of a VEGF peptide to electrospun scaffolds for potential applications in angiogenesis. Bioactive Materials, 20(1), 306-317. https://doi.org/10.1016/j.bioactmat.2022.05.029
    • Beukenhorst, A. L., Frallicciardi, J., Koch, C. M., Klap, J. M., Phillips, A., Desai, M. M., Wichapong, K., Nicolaes, G. A. F., Koudstaal, W., Alter, G., & Goudsmit, J. (2023). Corrigendum: The influenza hemagglutinin stem antibody CR9114: Evidence for a narrow evolutionary path towards universal protection ( vol 2 , 1049134 , 2022). Frontiers in Virology, 3, Article 1130102. https://doi.org/10.3389/fviro.2023.1130102
    • van Smaalen, T. C., Beurskens, D. M. H., Kox, J. J. H. F. M., Polonia, R., Vos, R., Duimel, H., van de Wetering, W. J., Lopez-Iglesias, C., Reutelingsperger, C. P., van Heurn, L. W. E., Peutz-Kootstra, C. J., & Nicolaes, G. A. F. (2023). Extracellular histone release by renal cells after warm and cold ischemic kidney injury: Studies in an ex-vivo porcine kidney perfusion model. PLOS ONE, 18(1), Article e0279944. https://doi.org/10.1371/journal.pone.0279944
    • Heuts, S., Gollmann-Tepeköylü, C., Denessen, E. J. S., Olsthoorn, J. R., Romeo, J. L. R., Maessen, J. G., van 't Hof, A. W. J., Bekers, O., Hammarsten, O., Pölzl, L., Holfeld, J., Bonaros, N., van der Horst, I. C. C., Davidson, S. M., Thielmann, M., & Mingels, A. M. A. (2023). Cardiac troponin release following coronary artery bypass grafting: mechanisms and clinical implications. European Heart Journal, 44(2), 100-112. https://doi.org/10.1093/eurheartj/ehac604
    • Moore, G. W., Castoldi, E., Teruya, J., Morishita, E., & Adcock, D. M. (2023). Factor V Leiden-independent activated protein C resistance: Communication from the plasma coagulation inhibitors subcommittee of the International Society on Thrombosis and Haemostasis Scientific and Standardisation Committee. Journal of Thrombosis and Haemostasis, 21(1), 164-174. https://doi.org/10.1016/j.jtha.2022.10.014
    • Dzhanaev, R., Hasberg, C., Gorgels, A., Schmitz, C., Winkler, C. F., Malyaran, H., Graeber, S., Gentier, A., Jaminon, A., Agten, S., Hackeng, T., Akbulut, A. C., Schurgers, L., Mottaghy, F. M., Goettsch, C., & Jahnen-Dechent, W. (2023). Application of the mineral-binding protein fetuin-A for the detection of calcified lesions. Theranostics, 13(2), 659-672. https://doi.org/10.7150/thno.78773
  • 2022
    • Beghi, S., Furmanik, M., Jaminon, A., Veltrop, R., Rapp, N., Wichapong, K., Bidar, E., Buschini, A., & Schurgers, L. J. (2022). Calcium Signalling in Heart and Vessels: Role of Calmodulin and Downstream Calmodulin-Dependent Protein Kinases. International journal of molecular sciences, 23(24), Article 16139. https://doi.org/10.3390/ijms232416139
    • Denessen, E. J., Heuts, S., Daemen, J. H., van Doorn, W. P., Vroemen, W. H., Sels, J.-W., Segers, P., Van't Hof, A. W., Maessen, J. G., Bekers, O., Van Der Horst, I. C., & Mingels, A. M. (2022). High-Sensitivity Cardiac Troponin I and T Kinetics Differ following Coronary Bypass Surgery: A Systematic Review and Meta-Analysis. Clinical Chemistry, 68(12), 1564-1575. Article hvac152. https://doi.org/10.1093/clinchem/hvac152
    • Kemp, J. A., Alvarenga, L., Cardozo, L. F. M. F., Dai, L., Stenvinkel, P., Shiels, P. G., Hackeng, T. M., Schurgers, L. J., & Mafra, D. (2022). Dysbiosis in Patients with Chronic Kidney Disease: Let Us Talk About Vitamin K. Current nutrition reports, 11(4), 765-779. https://doi.org/10.1007/s13668-022-00438-9